FPR2 anticorps (C-Term)

N° du produit ABIN5540337

L’anticorps Lapin Polyclonal anti-FPR2 a été validé pour WB, IF et ICC. Il convient pour détecter FPR2 dans des échantillons de Humain.

Aperçu rapide pour FPR2 anticorps (C-Term) (ABIN5540337)

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FPR2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-FPR2 anticorps

Épitope: C-Term

Séquence: SASPPAETEL QAM

Specificité: This antibody reacts with Human formyl peptide receptor-like 1.

Immunogène: A short peptide corresponding to the C-terminal amino acid sequence on FPRL1 was conjugated with KLH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Buffer System: 0.01M PBS, pH 7.2

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur FPR2

Antigène: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Autre désignation: fpr2,fprl1

Sujet: Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-α by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.